Enzyme/yeast-based prebiotic for poultry nutrition

Principal Investigator - Bogdan Slominski, University of Manitoba
Year the work was done - 2013-2017
Overall objective - To investigate the potential for a combination of an existing multicarbohydrase preparation fortified with a yeast cell wall lytic activity and the yeast derived product(s) as an effective and inexpensive alternative to antibiotics.

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Non-antibiotic control of bacterial infection

Principal Investigator - Mohammed Arshud Dar, University of Saskatchewan
Year the work was done - 2013-2017
Overall objective - To develop a non-antibiotics based in ovo effective, safe and economical strategy to prevent bacterial infections causing early chick mortalities and yolk sac infection (YSI).

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Evaluation of butyrate glycerides for developing an alternative to dietary antibiotics in poultry

Principal Investigator - Joshua Gong, Agriculture and Agri-Food Canada
Year the work was done - 2014-2016
Overall objective - To evaluate the potential of butyrate glycerides as an alternative to dietary antibiotics to enhance chicken growth performance.

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Alternative antimicrobials from chicken blood

Principal Investigator - Max Hincke, University of Ottawa
Year the work was done - 2014-2017
Overall objective - To purify and validate poultry histones purified from red blood cells as an alternative antimicrobial agent, in order to increase the value of abattoir blood for the turkey, chicken broiler and layer (spent-hen) industries.

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Novel bioactives of yeast: enzymatic release, identification and their prebiotic effects

Principal Investigator - Bogdan Slominski, University of Manitoba
Year the work was done - 2019-2023
Overall objective - Enhance the biological activity of yeast and yeast-derived products and to determine the effect of enzyme-modified yeast bioactives on gastrointestinal tract development, immune system function, their prebiotic effects in modifying the microbiome composition, minimizing pathogenic bacteria colonization (i.e., Salmonella, C. perfringens), and thus improving the growth performance of poultry.

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Non-antibiotic control of bacterial infections in poultry

Principal Investigator - Arshud Dar, University of Saskatchewan; Wolfgang Köster, University of Saskatchewan
Year the work was done - 2018-2023
Overall objective - To develop and characterize non-antibiotics based in ovo and post hatch effective, safe and economical strategies for control of bacterial infections in poultry.

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Investigations into synergistic effects of butyrate glycerides with plant extracts for reducing the use of antibiotics in chicken production

Principal Investigator - Joshua Gong, Agriculture and Agri-Food Canada; Shayan Sharif, University of Guelph; Bruce Rathgeber, Dalhousie University
Year the work was done - 2018-2023
Overall objective - To investigate synergistic effects of butyrate glycerides with plant extracts to promote chicken growth performance and to control necrotic enteritis in chickens.

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Optimizing antibiotics free preventative strategy using vaccines and probiotics for controlling necrotic enteritis in chickens

Principal Investigator - Susantha Gomis, University of Saskatchewan
Year the work was done - 2018-2023
Overall objective - Develop a strategy for controlling necrotic enteritis in chickens using novel vaccines and probiotics formulated in our lab while comparing and combining them with an autogenous vaccine (will be prepared by VECCI-VET Inc.) and commercially available probiotics (PoultryStar®) options available in Canada.

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Assessment of FadV-9 based vectored vaccine expressing NetB antigen in protection against necrotic enteritis in chickens

Principal Investigator - Éva Nagy, University of Guelph
Year the work was done - 2018-2020
Overall objective - Analysis of fowl adenovirus 9 based recombinants containing the netB gene of Campylobacter perfringens (in vitro studies, and evaluation of the recombinants by immunization and challenge studies of chickens (in vivo studies).

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