A comparative and subtractive reverse vaccinology approach to develop an in ovo vaccine against Clostridium perfringens


Principal Investigator

Martine Boulianne, University of Montreal; Joshua Gong, Agriculture and Agri-Food Canada

Year the work was done

2018-2023

Overall objective

  • The main objective is to develop an efficacious vaccine. But given the paucity of current knowledge in the area of C. perfringens and NE pathogenesis and control, the research will yield fundamental new knowledge in these areas.

Specific objectives

  • In the longer term, this research will provide a basis for immune intervention strategies for the control of NE in chickens, which is prevalent in Canada and globally, causing significant economic losses to broiler, broiler breeders and laying hens housed in aviaries.

This research applies to

Breeders, Broilers, Hatcheries, Layers, Turkeys

This research was supported by Agriculture and Agri-Food Canada, Canadian Poultry Research Council, Fondation Claire et Jean-Pierre Léger, and National Sciences and Engineering Research Council of Canada.