Determining the molecular basis of adaptation of influenza viruses from their natural reservoir to domestic poultry

Principal Investigator

Yohannes Berhane, Canadian Food Inspection Agency

Year the work was done


Overall objective

  • To better understand how avian influenza virus has developed the ability to infect domestic poultry.


  • Many so-called “reassortment” viruses have been developed and are being characterized with respect to a number of biological properties including the ability to induce immune responses and cause disease in chickens.


  • This research is part of an overall program to better understand the biology of avian influenza with the long-term goal of developing rational control strategies in domestic poultry.

This research applies to

Breeders, Broilers, Layers, Turkeys

This research was supported by Agriculture and Agri-Food Canada, Canadian Poultry Research Council and Canadian Food Inspection Agency.