Developing novel vaccines against AIV and exploring efficient delivery systems for these vaccines

Principal Investigator - Éva Nagy, University of Guelph
Year the work was done - 2010-2013
Overall objective - To further develop fowl adenovirus-based vectors and determine their potential to generate replication-competent recombinant vaccines.

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Developing novel vaccines against AIV and exploring efficient delivery systems for these vaccines

Principal Investigator - Suresh Tikko, VIDO-Intervec
Year the work was done - 2010-2013
Overall objective - To develop alternative vaccines for avian influenza.

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Developing novel vaccines against AIV and exploring efficient delivery systems for these vaccines

Principal Investigator - Dele Ogunrami, Canadian Food Inspection Agency
Year the work was done - 2010-2013
Overall objective - To develop DNA-based avian influenza vaccine platform, and assess the safety and efficacy of needle-free delivery methods for adenovirus-, virosome- and DNA-based vaccines.

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Assessment of FadV-9 based vectored vaccine expressing netB antigen in protection against necrotic enteritis in chickens

Principal Investigator - Éva Nagy, University of Guelph
Year the work was done - 2018-2020
Overall objective - Analyze fowl adenovirus 9 based recombinants containing the netB gene of Campylobacter perfringens (in vitro studies) and evaluate of the recombinants by immunization and challenge studies of chickens (in vivo studies).

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Innovations in antimicrobial alternatives and stewardship in poultry production

Principal Investigator - Shayan Sharif, University of Guelph; Doug Korver, University of Alberta; Juan Carlos Rodriguez-Lecompte, University of Prince Edward Island; Joshua Gong, Agriculture and Agri-Food Canada
Year the work was done - 2018-2023
Overall objective - Design, construct and develop a feasible and effective necrotic enteritis (NE) vaccine strategy in chickens.

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Optimizing antibiotics free preventative strategy using vaccines and probiotics for controlling necrotic enteritis in chickens

Principal Investigator - Susantha Gomis, University of Saskatchewan
Year the work was done - 2018-2023
Overall objective - Develop a strategy for controlling necrotic enteritis in chickens using novel vaccines and probiotics formulated in our lab while comparing and combining them with an autogenous vaccine (will be prepared by VECCI-VET Inc.) and commercially available probiotics (PoultryStar®) options available in Canada.

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Efficacy of new vaccine strategies to protect broiler chickens against necrotic enteritis

Principal Investigator - Martine Boulianne, University of Montreal
Year the work was done - 2018-2021
Overall objective - This project proposes to target two different innovative approaches (membrane vesicles of C. perfringens and bacteriocins) as potential and effective vaccine strategies against necrotic enteritis (NE)

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A comparative and subtractive reverse vaccinology approach to develop an in ovo vaccine against Clostridium perfringens

Principal Investigator - Martine Boulianne, University of Montreal; Joshua Gong, Agriculture and Agri-Food Canada
Year the work was done - 2018-2023
Overall objective - The main objective is to develop an efficacious vaccine. But given the paucity of current knowledge in the area of C. perfringens and NE pathogenesis and control, the research will yield fundamental new knowledge in these areas.

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Assessment of impact of Canadian infectious bronchitis virus (IBV) variants on egg production and fertility in chickens

Principal Investigator - Mohamed Faizal Abdul Careem, University of Calgary
Year the work was done - 2018-2023
Overall objective - Quantify the impact of IBV variants on egg production and propose mitigation strategies for the variants the impact layer flocks in Canada.

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