Rationale-based mitigation of relevant Campylobacter jejuni strains within the broiler production continuum


Principal Investigator

Doug Inglis, Agriculture and Agri-Food Canada

Year the work was done

2018-2023

Overall objective

  • A multi-faceted approach to mitigate relevant Campylobacter jejuni (Cj) strains within the broiler production system.

Specific objectives

  • Identify Cj strains associated with poultry production and processing operations in Canada, including the identification of clinically relevant (CR) Cj strains.
  • Determine important reservoirs and mechanisms by which Cj strains enter broiler operational housing units and are transmitted throughout the continuum.
  • Experimentally ascertain the mechanisms involved in infection and colonization of birds by Cj strains, and their transmission within flocks.
  • Elucidate key phenotypic characteristics of CR Cj strains (e.g. that permit them to competitively colonize the gastrointestinal tract of chickens and persist extra-intestinally.
  • Develop effective diagnostics for CR Cj for use by the sector.
  • Explore effective mitigation of CR Cj within abattoirs and on farm.
  • Protect intellectual property and develop and implement a knowledge translation and commercialization plan to optimize benefits to producers.

This research applies to

Broilers

This research was supported by Agriculture and Agri-Food Canada, Canadian Poultry Research Council and Alberta Chicken Producers.